Ca-free contraction in Na-free system in rat uterine smooth muscle
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چکیده
منابع مشابه
Novel role for K -dependent Na /Ca exchangers in regulation of cytoplasmic free Ca and contractility in arterial smooth muscle
Hui Dong, Yanfen Jiang, Chris R. Triggle, Xiaofang Li, and Jonathan Lytton Division of Gastroenterology, Department of Medicine, University of California, San Diego School of Medicine, San Diego, California; and Department of Pharmacology and Therapeutics and Department of Biochemistry and Molecular Biology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada
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The inhibition of myosin phosphatase evokes smooth muscle contraction in the absence of Ca(2+), yet the underlying mechanisms are not understood. To this end, we have cloned smooth muscle zipper-interacting protein (ZIP) kinase cDNA. ZIP kinase is present in various smooth muscle tissues including arteries. Triton X-100 skinning did not diminish ZIP kinase content, suggesting that ZIP kinase as...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1988
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)57310-3